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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24263.1Transcriptional regulator, BadM/Rrf2 family; PFAM: amino acid-binding ACT domain protein; Helix-turn-helix type 11 domain protein; protein of unknown function UPF0074; KEGG: dal:Dalk_5107 (p)ppGpp synthetase I, SpoT/RelA. (145 aa)    
Predicted Functional Partners:
ACV24264.1
TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: ppr:PBPRB0776 putative adenylate cyclase CyaB.
       0.906
ACV24262.1
TIGRFAM: Asp/Glu amidotransferase, subunit C.
       0.435
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
       0.415
rps17e
KEGG: 40S ribosomal protein S17-A; K02962 small subunit ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.
       0.404
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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