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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24305.1PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dps:DP2755 ferredoxin III. (82 aa)    
Predicted Functional Partners:
ACV24306.1
Enolase-like protein; KEGG: wri:WRi_002510 enolase.
 
   
 0.725
ACV25047.1
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: vap:Vapar_5615 fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
  
 
 0.653
ACV25181.1
TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain protein; PFAM: CoA-binding domain protein; KEGG: dal:Dalk_1024 acetyl coenzyme A synthetase (ADP forming), alpha domain protein.
     
 0.629
ACV24307.1
PFAM: RNA polymerase Rpb6; KEGG: RNA polymerase I, II, III common subunit; K03014 DNA-directed RNA Polymerase II subunit F.
       0.624
ACV25139.1
Phosphate uptake regulator, PhoU; PFAM: PhoU family protein; KEGG: cti:RALTA_A1971 negative regulator of PhoR/PhoB two-component regulator.
 
     0.557
ACV24037.1
TIGRFAM: pyridoxal phosphate enzyme; KEGG: spl:Spea_0442 selenocysteine synthase.
 
     0.554
ACV25137.1
PFAM: Queuosine synthesis-like; KEGG: cjd:JJD26997_1992 hypothetical protein.
  
     0.478
ACV24193.1
PFAM: Cobyrinic acid ac-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase; KEGG: gur:Gura_0041 cobyric acid synthase CobQ.
 
   
 0.468
ACV23975.1
PFAM: protein of unknown function DUF129.
  
     0.401
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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