Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24306.1Enolase-like protein; KEGG: wri:WRi_002510 enolase. (314 aa)    
Predicted Functional Partners:
ACV24307.1
PFAM: RNA polymerase Rpb6; KEGG: RNA polymerase I, II, III common subunit; K03014 DNA-directed RNA Polymerase II subunit F.
  
  
 0.981
pgk
PFAM: phosphoglycerate kinase; KEGG: ade:Adeh_1531 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 
 
 0.965
rps9
TIGRFAM: ribosomal protein S9P; PFAM: ribosomal protein S9; KEGG: hypothetical protein; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.965
gap
Glyceraldehyde-3-phosphate dehydrogenase, type II; KEGG: ajs:Ajs_2165 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase.
  
 
 0.961
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.961
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
 
 
 0.926
rps11
Ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 
 0.903
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: afw:Anae109_2086 glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.902
ACV24180.1
KEGG: nis:NIS_1773 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 
 0.898
ACV24312.1
PFAM: RNA polymerase insert; RNA polymerase dimerization; SMART: RNA polymerase RpoA/D/Rpb3-type; KEGG: DNA-directed RNA polymerases I and III 40 kDa polypeptide; K03027 DNA-directed RNA Polymerase III subunit C5.
  
  
 0.893
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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