Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24340.1PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ret:RHE_CH00772 putative methyltransferase protein. (222 aa)    
Predicted Functional Partners:
ACV24338.1
PFAM: glycosyl transferase family 9; KEGG: cff:CFF8240_1403 putative heptosyltransferase III WaaQ.
 
     0.784
ACV24339.1
PFAM: glycosyl transferase family 9; KEGG: sde:Sde_1100 lipopolysaccharide heptosyltransferase-1, putative.
 
     0.766
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
    
 0.722
rps9
TIGRFAM: ribosomal protein S9P; PFAM: ribosomal protein S9; KEGG: hypothetical protein; Belongs to the universal ribosomal protein uS9 family.
    
 0.612
ACV24342.1
PFAM: glycosyl transferase family 2; KEGG: sfu:Sfum_3546 glycosyl transferase, family 2.
 
 
 
 0.559
rpl7ae
Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 0.557
ACV24341.1
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: cja:CJA_0067 cyclopropane-fatty-acyl-phospholipid synthase.
 
    
0.531
rps19e
Ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
   
 0.529
rps6e
PFAM: Ribosomal protein S6e; KEGG: 40S ribosomal protein S6; K02991 small subunit ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 0.525
flpA
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.525
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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