Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (185 aa)    
Predicted Functional Partners:
ACV24351.1
TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: nis:NIS_1450 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase.
  
 0.997
ACV24353.1
TIGRFAM: rfaE bifunctional protein; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; KEGG: nis:NIS_1448 ADP-heptose synthase.
      0.990
ACV25317.1
PFAM: glycosyl transferase group 1; Starch synthase catalytic domain protein; KEGG: probabale LPS (Lipopolysaccharide) glycosyltransferase.
 
  
 0.885
ACV24352.1
PFAM: PfkB domain protein; KEGG: hypothetical protein LOC100197396.
   
 0.782
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 0.751
ACV24355.1
TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: gme:Gmet_1159 UDP-glucose pyrophosphorylase.
     
 0.662
ACV24138.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: wbr:WGLp587 asparagine synthetase B.
       0.581
ACV24347.1
Nucleotide sugar dehydrogenase; KEGG: mxa:MXAN_1048 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerization; UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein.
     
 0.512
ACV24598.1
PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: fph:Fphi_0366 UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase.
  
  
 0.476
ACV24346.1
PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KEGG: cju:C8J_1346 hypothetical protein.
  
  
 0.443
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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