Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACV24359.1TIGRFAM: alpha-ribazole phosphatase CobZ; PFAM: phosphatidylglycerophosphatase A; KEGG: hpa:HPAG1_0721 phosphatidylglycerophosphatase A. (145 aa)    
Predicted Functional Partners:
ACV24138.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: wbr:WGLp587 asparagine synthetase B.
 
   
 0.866
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.848
ACV24137.1
GTP:adenosylcobinamide-phosphate guanylyltransferase-like protein; KEGG: ara:Arad_0036 nucleotidyltransferase protein.
 
     0.761
ACV25249.1
PFAM: phosphoesterase PA-phosphatase related; SNARE associated Golgi protein; SMART: phosphoesterase PA-phosphatase related; KEGG: dps:DP0274 hypothetical protein.
 
  
 0.735
ACV24244.1
Conserved hypothetical protein.
  
     0.625
ACV24147.1
PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; KEGG: abu:Abu_2184 hypothetical protein; Belongs to the UPF0284 family.
 
     0.593
ACV24360.1
PFAM: DEAD/DEAH box helicase domain protein; Protein of unknown function DUF1998; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: dal:Dalk_2442 DEAD/DEAH box helicase domain protein.
       0.590
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
   
 0.577
ACV24403.1
PFAM: Protein of unknown function DUF61; Belongs to the UPF0216 family.
 
     0.544
ACV25125.1
TIGRFAM: methanogenesis marker protein 3; Belongs to the UPF0288 family.
 
     0.527
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.