Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24373.1S-layer domain protein-like protein; KEGG: bpt:Bpet0291 hypothetical protein. (558 aa)    
Predicted Functional Partners:
ACV24374.1
Exporter of the RND superfamily protein-like protein; KEGG: mxa:MXAN_0441 hypothetical protein.
 
  
 0.962
ACV24375.1
PFAM: regulatory protein ArsR; transcriptional regulator TrmB; KEGG: dac:Daci_2400 ArsR family transcriptional regulator; Belongs to the GbsR family.
       0.935
ACV24377.1
PFAM: 4-oxalocrotonate tautomerase; KEGG: gme:Gmet_1510 4-oxalocrotonate tautomerase.
       0.722
ACV24376.1
PFAM: formylmethanofuran dehydrogenase subunit E region; KEGG: dal:Dalk_3123 formylmethanofuran dehydrogenase subunit E region.
  
    0.719
ACV24372.1
PFAM: major facilitator superfamily MFS_1; KEGG: dal:Dalk_2388 major facilitator superfamily MFS_1.
 
    0.690
ACV25013.1
PFAM: Peptidase A24B, FlaK domain protein; peptidase A24A prepilin type IV; KEGG: shl:Shal_2284 peptidase A24A prepilin type IV.
 
     0.676
ACV24849.1
Transcriptional regulator, MarR family; PFAM: regulatory protein ArsR; regulatory protein MarR; SMART: regulatory protein ArsR; KEGG: ank:AnaeK_0686 general secretion pathway protein-related protein.
  
     0.665
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
     0.661
ACV24122.1
PFAM: chromosome segregation and condensation protein ScpA; KEGG: hypothetical protein LOC691864.
  
     0.627
ACV24844.1
PFAM: Type II secretion system F domain; KEGG: pag:PLES_46811 TadB.
 
     0.621
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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