Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24375.1PFAM: regulatory protein ArsR; transcriptional regulator TrmB; KEGG: dac:Daci_2400 ArsR family transcriptional regulator; Belongs to the GbsR family. (167 aa)    
Predicted Functional Partners:
ACV24374.1
Exporter of the RND superfamily protein-like protein; KEGG: mxa:MXAN_0441 hypothetical protein.
       0.971
ACV24373.1
S-layer domain protein-like protein; KEGG: bpt:Bpet0291 hypothetical protein.
       0.935
ACV24376.1
PFAM: formylmethanofuran dehydrogenase subunit E region; KEGG: dal:Dalk_3123 formylmethanofuran dehydrogenase subunit E region.
       0.789
ACV24377.1
PFAM: 4-oxalocrotonate tautomerase; KEGG: gme:Gmet_1510 4-oxalocrotonate tautomerase.
       0.785
ACV24372.1
PFAM: major facilitator superfamily MFS_1; KEGG: dal:Dalk_2388 major facilitator superfamily MFS_1.
       0.574
ACV24104.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: hypothetical protein.
       0.501
carS
Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
       0.501
ACV24371.1
PFAM: Protein of unknown function DUF54; KEGG: hypothetical protein; Belongs to the UPF0201 family.
       0.437
ACV24370.1
PFAM: protein of unknown function DUF87; HerA-ATP synthase, barrel domain; KEGG: pag:PLES_23631 protein of unknown function DUF87.
       0.417
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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