Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24391.1PFAM: RNA polymerase Rpb4. (107 aa)    
Predicted Functional Partners:
rpoL
RNA polymerase dimerization; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
 
 
 
 0.971
rpoP
RNA polymerase Rbp10; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
  
 
 0.963
rpoH
RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
   
 
 0.960
rpoA2
DNA-directed RNA polymerase, subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.958
ACV25071.1
PFAM: RNA polymerase beta subunit; RNA polymerase Rpb2 domain 2; RNA polymerase Rpb2 domain 3; KEGG: hypothetical protein LOC100252267; K03010 DNA-directed RNA polymerase II subunit B.
  
 
 0.957
ACV24690.1
KEGG: hypothetical protein; K03022 DNA-directed RNA polymerase III subunit C25; TIGRFAM: DNA-directed RNA polymerase; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein.
   
 
 0.956
ACV25073.1
DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.953
ACV24307.1
PFAM: RNA polymerase Rpb6; KEGG: RNA polymerase I, II, III common subunit; K03014 DNA-directed RNA Polymerase II subunit F.
  
 
 0.951
ACV24312.1
PFAM: RNA polymerase insert; RNA polymerase dimerization; SMART: RNA polymerase RpoA/D/Rpb3-type; KEGG: DNA-directed RNA polymerases I and III 40 kDa polypeptide; K03027 DNA-directed RNA Polymerase III subunit C5.
    
 
 0.948
ACV25072.1
DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.945
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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