Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24403.1PFAM: Protein of unknown function DUF61; Belongs to the UPF0216 family. (132 aa)    
Predicted Functional Partners:
ACV24404.1
Hypothetical protein.
       0.980
ACV24405.1
Hypothetical protein.
       0.923
ACV24406.1
PFAM: glycosyl transferase family 2; KEGG: sun:SUN_1537 glycosyl transferase.
       0.915
atpF
Vacuolar H+transporting two-sector ATPase F subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
     0.724
atpE
H+transporting two-sector ATPase E subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
     0.645
ACV25114.1
PFAM: ATP dependent DNA ligase; KEGG: noc:Noc_1413 ATP-dependent DNA ligase.
  
     0.626
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily.
  
     0.614
ACV24657.1
Protein of unknown function UPF0278; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
  
     0.607
ACV25098.1
PFAM: TOPRIM domain protein; SMART: Toprim sub domain protein; Belongs to the UPF0292 family.
  
     0.564
ACV24402.1
PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: acp:A2cp1_3392 protein of unknown function DUF190.
       0.546
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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