Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24410.1PFAM: protein of unknown function DUF190; KEGG: gem:GM21_0715 protein of unknown function DUF190. (112 aa)    
Predicted Functional Partners:
ACV24411.1
PFAM: Oligosaccharyl transferase STT3 subunit; KEGG: nam:NAMH_1652 oligosaccharyl transferase, STT3 subunit.
       0.981
crcB
CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
 
   
 0.930
ACV24408.1
TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: dde:Dde_0803 precorrin-6Y C5,15-methyltransferase (decarboxylating).
 
     0.814
ACV24412.1
PFAM: protein of unknown function DUF111; KEGG: sat:SYN_00476 hypothetical protein; Belongs to the LarC family.
       0.651
ACV23903.1
KEGG: gbm:Gbem_1667 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein.
       0.609
ACV24413.1
Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family.
       0.594
ACV24407.1
TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; KEGG: afr:AFE_2544 geranylgeranyl reductase family protein.
       0.562
ACV24414.1
TIGRFAM: SagB-type dehydrogenase domain; PFAM: nitroreductase; KEGG: sfu:Sfum_0229 nitroreductase.
       0.519
ACV24415.1
PFAM: TatD-related deoxyribonuclease; KEGG: mxa:MXAN_1382 TatD family hydrolase.
       0.443
ACV25143.1
PFAM: Cl- channel voltage-gated family protein; KEGG: dat:HRM2_22170 EriC2.
 
     0.424
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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