Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACV24418.1PFAM: TrkA-N domain protein; Ion transport 2 domain protein; TrkA-C domain protein; KEGG: dal:Dalk_2078 TrkA-N domain protein. (340 aa)    
Predicted Functional Partners:
ACV24419.1
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; KEGG: DNA double-strand break repair Rad50 ATPase; K02349 DNA polymerase theta subunit.
  
    0.937
ACV24417.1
TIGRFAM: methylase; PFAM: methyltransferase small; Methyltransferase type 11; Methyltransferase type 12; KEGG: hypothetical protein.
       0.723
ACV24420.1
Hypothetical protein.
       0.723
ACV24909.1
PFAM: phosphoesterase RecJ domain protein; RNA binding S1 domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: dat:HRM2_01850 RecJ-like exonuclease (DnaJ-type Zn finger protein).
     
 0.648
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily.
       0.620
ACV24416.1
PFAM: protein of unknown function DUF34; KEGG: dal:Dalk_3075 protein of unknown function DUF34.
     
 0.552
ACV24421.1
Dephospho-CoA kinase-like protein; KEGG: hypothetical protein; Belongs to the UPF0200 family.
       0.516
ACV25322.1
TIGRFAM: small GTP-binding protein; PFAM: TGS domain protein; GTP-binding protein HSR1-related; KEGG: hypothetical protein.
     
 0.418
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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