Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24427.1TIGRFAM: ammonium transporter; PFAM: ammonium transporter; KEGG: gem:GM21_1136 Rh family protein/ammonium transporter. (383 aa)    
Predicted Functional Partners:
ACV24428.1
PFAM: nitrogen regulatory protein P-II; KEGG: abu:Abu_0198 nitrogen regulatory protein PII; Belongs to the P(II) protein family.
 
 0.999
ACV24138.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: wbr:WGLp587 asparagine synthetase B.
  
  
 0.901
ACV24014.1
KEGG: dat:HRM2_45740 GlnA2; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
  
  
 0.839
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
  
  
 0.758
ACV24426.1
PFAM: sodium/hydrogen exchanger; KEGG: cja:CJA_2911 putative pH regulated Na(+)/H(+) antiporter.
 
  
 0.703
ACV24018.1
PFAM: ferredoxin-dependent glutamate synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dvu:DVU1823 glutamate synthase, iron-sulfur cluster-binding subunit, putative; Belongs to the glutamate synthase family.
 
  
 0.669
ACV24019.1
PFAM: glutamine amidotransferase class-II; KEGG: dde:Dde_1815 glutamate synthase (NADPH) GltB1 subunit.
     
 0.582
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
     
 0.565
ribK
CTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
       0.528
ACV24469.1
PFAM: formate/nitrite transporter; KEGG: sat:SYN_01200 formate/nitrite transporter family protein.
   
  
 0.526
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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