Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24436.1PFAM: aminotransferase class I and II; KEGG: dal:Dalk_3407 aspartate aminotransferase. (374 aa)    
Predicted Functional Partners:
ACV24514.1
PFAM: aspartate/glutamate/uridylate kinase; KEGG: noc:Noc_0254 amino acid kinase family protein.
    
 0.905
mfnB
Protein of unknown function DUF556; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
     
 0.903
ACV24085.1
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: nmu:Nmul_A2192 chorismate mutase.
 
  
 0.895
rtcB
PFAM: protein of unknown function UPF0027; KEGG: sat:SYN_02046 RtcB protein; Belongs to the RtcB family.
  
    0.610
ACV24435.1
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: dal:Dalk_1102 cobyrinic acid ac-diamide synthase.
     
 0.552
ACV24434.1
PFAM: Protein of unknown function UPF0146; Belongs to the UPF0146 family.
       0.546
ACV24138.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: wbr:WGLp587 asparagine synthetase B.
  
  
 0.542
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
  
 0.503
ACV24152.1
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rlt:Rleg2_5063 homoserine dehydrogenase.
 
 
 0.461
ACV24438.1
PFAM: Transketolase domain protein; KEGG: gur:Gura_0491 transketolase domain-containing protein.
     
 0.461
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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