Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24441.1TIGRFAM: uncharacterized hydrophobic domain protein; PFAM: conserved hypothetical protein; KEGG: dal:Dalk_0015 hypothetical protein. (319 aa)    
Predicted Functional Partners:
ACV24440.1
PFAM: Transketolase central region; Transketolase domain protein; KEGG: gme:Gmet_0552 transketolase subunit B.
       0.666
ACV24439.1
KEGG: ade:Adeh_3971 ribulose-5-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
       0.600
pdxS
Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
       0.559
ACV24438.1
PFAM: Transketolase domain protein; KEGG: gur:Gura_0491 transketolase domain-containing protein.
       0.540
ACV25332.1
PFAM: protein of unknown function UPF0132; KEGG: hha:Hhal_1506 hypothetical protein.
  
     0.423
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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