Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24451.1PFAM: PUA domain containing protein; SMART: PUA domain containing protein. (535 aa)    
Predicted Functional Partners:
ACV24452.1
KEGG: viral A-type inclusion protein.
  
    0.982
tgtA
Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
 
 
0.931
ACV24614.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: ftf:FTF0287c hypothetical protein.
 
     0.848
ACV24106.1
PFAM: NMD3 family protein.
  
     0.703
rpl40e
Hypothetical protein; Belongs to the eukaryotic ribosomal protein eL40 family.
  
     0.686
ACV24129.1
PFAM: TatD-related deoxyribonuclease.
  
     0.676
ACV25131.1
PFAM: Protein of unknown function UPF0179; Belongs to the UPF0179 family.
  
     0.672
ACV24719.1
PFAM: transcriptional regulator TrmB; KEGG: ecr:ECIAI1_1939 conserved hypothetical protein; CymJ protein, transcriptional regulator domain.
 
     0.622
ACV25284.1
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
  
     0.603
ACV25177.1
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: similar to multiprotein bridging factor 1 CG4143-PA, isoform A; K03627 putative transcription factor.
  
     0.595
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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