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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24459.1CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; P2 response regulator binding domain protein; SMART: Hpt domain protein; ATP-binding region ATPase domain protein; CheW domain protein; KEGG: nam:NAMH_0362 chemotaxis protein CheA. (969 aa)    
Predicted Functional Partners:
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.999
ACV24461.1
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: dma:DMR_10020 chemotaxis protein CheW.
 
 
 0.999
cheD
CheD, stimulates methylation of MCP protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  
 0.997
ACV24921.1
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: ank:AnaeK_4453 response regulator receiver protein.
 
 
 0.996
ACV24923.1
PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: psb:Psyr_2188 histidine kinase, HAMP region: chemotaxis sensory transducer:CHASE3.
 
 
 0.981
ACV23867.1
PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: dma:DMR_07730 methyl-accepting chemotaxis protein.
 
 
 0.980
ACV24571.1
PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: sat:SYN_00432 methyl-accepting chemotaxis protein.
 
 
 0.980
ACV24918.1
KEGG: geo:Geob_0927 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase CheR-type; SMART: MCP methyltransferase CheR-type.
 
  
 0.861
ACV24920.1
PFAM: CheC domain protein; KEGG: gem:GM21_0635 CheC, inhibitor of MCP methylation.
 
  
 0.720
ACV24919.1
PFAM: CheC domain protein; KEGG: gem:GM21_0635 CheC, inhibitor of MCP methylation.
 
  
 0.704
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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