Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24468.1Hypothetical protein. (85 aa)    
Predicted Functional Partners:
ACV24470.1
Hypothetical protein.
  
    0.943
ACV24469.1
PFAM: formate/nitrite transporter; KEGG: sat:SYN_01200 formate/nitrite transporter family protein.
  
    0.938
ACV24471.1
PFAM: carbonic anhydrase; Carbonic anhydrase, YbcF-related; KEGG: gbm:Gbem_1887 carbonic anhydrase.
  
    0.933
ACV24472.1
Contains selenocysteine; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: ppd:Ppro_3520 formate dehydrogenase, alpha subunit.
  
    0.594
ACV24473.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfu:Sfum_0822 formate dehydrogenase.
  
    0.554
ACV24467.1
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: geo:Geob_1632 histidine kinase.
       0.495
ACV24466.1
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: dvl:Dvul_1155 response regulator receiver protein.
       0.490
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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