Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24485.1Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: tbd:Tbd_1388 hypothetical protein. (194 aa)    
Predicted Functional Partners:
tmk
KEGG: wpi:WPa_0905 thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: thymidylate kinase.
     
 0.952
ACV24402.1
PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: acp:A2cp1_3392 protein of unknown function DUF190.
 
   
0.895
ACV23924.1
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: dma:DMR_13800 two-component hybrid sensor and regulator.
 
   
0.829
rps2
TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; KEGG: RSP1; 40S ribosomal protein-like protein; K02998 small subunit ribosomal protein SAe; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.676
rpl21e
PFAM: Ribosomal protein L21e; KEGG: 60S ribosomal protein L21; K02889 large subunit ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
 
   0.671
rps13
Ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family.
  
 
 0.664
rps8e
TIGRFAM: ribosomal protein S8e; PFAM: Ribosomal protein S8E; KEGG: rps8-1; 40S ribosomal protein S8; K02995 small subunit ribosomal protein S8e.
  
 
   0.660
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.657
rpl13
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.653
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 
 0.652
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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