Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24515.1TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerization domain protein; KEGG: dma:DMR_26040 peptidase M20 family protein. (409 aa)    
Predicted Functional Partners:
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
 
  
 0.936
argD
KEGG: geo:Geob_1122 acetylornithine and succinylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; aminotransferase class I and II; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.936
ACV24707.1
PFAM: aminotransferase class I and II; KEGG: sfu:Sfum_0054 aminotransferase, class I and II.
    
 0.912
ACV24516.1
Hypothetical protein.
       0.903
ACV24514.1
PFAM: aspartate/glutamate/uridylate kinase; KEGG: noc:Noc_0254 amino acid kinase family protein.
       0.854
ACV24513.1
PFAM: Protein of unknown function DUF1610.
 
     0.757
ACV24138.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: wbr:WGLp587 asparagine synthetase B.
  
 
 0.754
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
 
 0.710
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
  
 0.614
ACV23852.1
KEGG: afw:Anae109_0787 beta-lactamase domain-containing protein.
       0.609
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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