| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACV24126.1 | eif5a | Mefer_0290 | Mefer_0578 | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | 0.832 |
| ACV24126.1 | pcn | Mefer_0290 | Mefer_0432 | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.469 |
| ACV24126.1 | pelA | Mefer_0290 | Mefer_0742 | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Translation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. | 0.778 |
| ACV24126.1 | pheT | Mefer_0290 | Mefer_1353 | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | phenylalanyl-tRNA synthetase, beta subunit; KEGG: frs-2; phenylalanyl (F) tRNA Synthetase; K01890 phenylalanyl-tRNA synthetase beta chain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5; B3/4 domain protein. | 0.794 |
| ACV24126.1 | rpl10 | Mefer_0290 | Mefer_0704 | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.720 |
| ACV24126.1 | rpl29 | Mefer_0290 | Mefer_0690 | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; KEGG: 60S ribosomal protein L35; K02918 large subunit ribosomal protein L35e; Belongs to the universal ribosomal protein uL29 family. | 0.450 |
| ACV24561.1 | pelA | Mefer_0743 | Mefer_0742 | DNA binding protein, Tfx family; Putative transcriptional regulator. | Translation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. | 0.916 |
| ACV24884.1 | ACV25096.1 | Mefer_1073 | Mefer_1287 | PFAM: ABC transporter related; 4Fe-4S ferredoxin iron-sulfur binding domain protein; metal-binding domain in RNase L inhibitor, RLI; SMART: AAA ATPase; KEGG: similar to ATP-binding cassette, sub-family E, member 1; K06174 ATP-binding cassette, sub-family E, member 1. | PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: hypothetical protein. | 0.567 |
| ACV24884.1 | pelA | Mefer_1073 | Mefer_0742 | PFAM: ABC transporter related; 4Fe-4S ferredoxin iron-sulfur binding domain protein; metal-binding domain in RNase L inhibitor, RLI; SMART: AAA ATPase; KEGG: similar to ATP-binding cassette, sub-family E, member 1; K06174 ATP-binding cassette, sub-family E, member 1. | Translation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. | 0.890 |
| ACV24884.1 | rpl10 | Mefer_1073 | Mefer_0704 | PFAM: ABC transporter related; 4Fe-4S ferredoxin iron-sulfur binding domain protein; metal-binding domain in RNase L inhibitor, RLI; SMART: AAA ATPase; KEGG: similar to ATP-binding cassette, sub-family E, member 1; K06174 ATP-binding cassette, sub-family E, member 1. | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.897 |
| ACV24884.1 | rpl29 | Mefer_1073 | Mefer_0690 | PFAM: ABC transporter related; 4Fe-4S ferredoxin iron-sulfur binding domain protein; metal-binding domain in RNase L inhibitor, RLI; SMART: AAA ATPase; KEGG: similar to ATP-binding cassette, sub-family E, member 1; K06174 ATP-binding cassette, sub-family E, member 1. | TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; KEGG: 60S ribosomal protein L35; K02918 large subunit ribosomal protein L35e; Belongs to the universal ribosomal protein uL29 family. | 0.806 |
| ACV24884.1 | tuf | Mefer_1073 | Mefer_1271 | PFAM: ABC transporter related; 4Fe-4S ferredoxin iron-sulfur binding domain protein; metal-binding domain in RNase L inhibitor, RLI; SMART: AAA ATPase; KEGG: similar to ATP-binding cassette, sub-family E, member 1; K06174 ATP-binding cassette, sub-family E, member 1. | Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.402 |
| ACV25096.1 | ACV24884.1 | Mefer_1287 | Mefer_1073 | PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: hypothetical protein. | PFAM: ABC transporter related; 4Fe-4S ferredoxin iron-sulfur binding domain protein; metal-binding domain in RNase L inhibitor, RLI; SMART: AAA ATPase; KEGG: similar to ATP-binding cassette, sub-family E, member 1; K06174 ATP-binding cassette, sub-family E, member 1. | 0.567 |
| ACV25096.1 | pcn | Mefer_1287 | Mefer_0432 | PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: hypothetical protein. | Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.489 |
| ACV25096.1 | pelA | Mefer_1287 | Mefer_0742 | PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: hypothetical protein. | Translation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. | 0.787 |
| ACV25096.1 | rpl10 | Mefer_1287 | Mefer_0704 | PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: hypothetical protein. | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.952 |
| ACV25096.1 | rpl29 | Mefer_1287 | Mefer_0690 | PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: hypothetical protein. | TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; KEGG: 60S ribosomal protein L35; K02918 large subunit ribosomal protein L35e; Belongs to the universal ribosomal protein uL29 family. | 0.942 |
| eif5a | ACV24126.1 | Mefer_0578 | Mefer_0290 | Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 0.832 |
| eif5a | pcn | Mefer_0578 | Mefer_0432 | Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.705 |
| eif5a | pelA | Mefer_0578 | Mefer_0742 | Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | Translation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. | 0.822 |
