Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24568.1PFAM: PP-loop domain protein; KEGG: hypothetical protein. (303 aa)    
Predicted Functional Partners:
ACV24567.1
PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: hypothetical protein; K07466 replication factor A1.
       0.921
ACV24566.1
TIGRFAM: cell division ATPase MinD; PFAM: Cobyrinic acid ac-diamide synthase; KEGG: nam:NAMH_1151 septum site-determining protein MinD.
     
 0.716
ACV25387.1
PFAM: PP-loop domain protein; KEGG: hypothetical protein.
  
  
 
0.664
ACV24959.1
Histone acetyltransferase, ELP3 family; KEGG: hypothetical protein; K07739 elongator complex protein 3; TIGRFAM: histone acetyltransferase, ELP3 family; PFAM: Radical SAM domain protein; GCN5-related N-acetyltransferase; SMART: Elongator protein 3/MiaB/NifB.
   
 
 0.660
ACV24966.1
PFAM: tRNA methyltransferase complex GCD14 subunit; KEGG: sfu:Sfum_2514 SAM-dependent methyltransferase.
 
  
 0.655
ACV24672.1
PFAM: peptidase M50; KEGG: geo:Geob_1515 membrane-associated zinc metalloprotease.
  
  
 0.629
ACV25265.1
PFAM: PP-loop domain protein; Queuosine synthesis-like; thiamine biosynthesis protein; KEGG: dma:DMR_30620 hypothetical protein.
  
  
 
0.603
ACV25276.1
PFAM: protein of unknown function Met10; methyltransferase small; KEGG: Met-10+ like family protein.
 
  
 0.592
ACV24569.1
Hypothetical protein.
       0.531
rlmE
Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
 
  
 0.480
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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