Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24614.1PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: ftf:FTF0287c hypothetical protein. (357 aa)    
Predicted Functional Partners:
ACV24451.1
PFAM: PUA domain containing protein; SMART: PUA domain containing protein.
 
     0.848
ACV24615.1
PFAM: nitrite and sulphite reductase 4Fe-4S region; 4Fe-4S ferredoxin iron-sulfur binding domain protein; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: gur:Gura_3941 nitrite and sulphite reductase 4Fe-4S region.
       0.773
ACV24616.1
TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: cvi:CV_1562 precorrin-3B C17-methyltransferase.
       0.752
rpl40e
Hypothetical protein; Belongs to the eukaryotic ribosomal protein eL40 family.
  
     0.678
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
 
     0.666
ACV24322.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dal:Dalk_2230 4Fe-4S ferredoxin iron-sulfur binding domain protein.
     
 0.624
ACV25131.1
PFAM: Protein of unknown function UPF0179; Belongs to the UPF0179 family.
  
     0.615
ACV23981.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dal:Dalk_1629 2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
       0.609
guaAB
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
       0.609
ACV24600.1
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: gur:Gura_2189 pyruvate ferredoxin/flavodoxin oxidoreductase.
       0.609
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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