Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24633.1KEGG: cbs:COXBURSA331_A1552 2-phosphosulfolactate phosphatase; TIGRFAM: 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulfolactate phosphatase. (224 aa)    
Predicted Functional Partners:
ACV23944.1
PFAM: (2R)-phospho-3-sulfolactate synthase ComA; KEGG: phosphosulfolactate synthase.
 
 
 0.990
rnp3
Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
 
     0.972
ACV25203.1
PFAM: Malate/L-lactate dehydrogenase; KEGG: sat:SYN_02526 malate/L-lactate dehydrogenase.
     
 0.964
ACV24298.1
PFAM: Protein of unknown function DUF371.
   
    0.831
ACV23942.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: sdn:Sden_1162 thiamine pyrophosphate enzyme-like TPP-binding.
      
 0.640
ACV24632.1
PFAM: protein of unknown function DUF116; KEGG: pca:Pcar_0243 hypothetical protein.
       0.615
ACV25159.1
TIGRFAM: TraB family protein; PFAM: TraB determinant protein; KEGG: dol:Dole_2685 TraB family protein.
       0.583
ACV24540.1
PFAM: Lactate/malate dehydrogenase; KEGG: ama:AM564 malate dehydrogenase; Belongs to the LDH/MDH superfamily.
    
 0.529
ACV24631.1
Arsenite-activated ATPase ArsA; KEGG: hypothetical protein; K01551 arsenite-transporting ATPase; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase.
       0.483
ACV24580.1
PFAM: protein of unknown function DUF752; KEGG: tdn:Suden_1933 hypothetical protein.
 
    0.478
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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