Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
ACV24653.1PFAM: protein of unknown function DUF124; KEGG: swd:Swoo_0459 hypothetical protein. (222 aa)    
Predicted Functional Partners:
ACV25285.1
TIGRFAM: hydroxymethylglutaryl-CoA synthase; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; Hydroxymethylglutaryl-coenzyme A synthase domain; KEGG: pfl:PFL_5954 hypothetical protein; Belongs to the thiolase-like superfamily. UPF0219 family.
     
 0.618
ACV25286.1
PFAM: Thiolase; KEGG: gur:Gura_4354 thiolase.
       0.606
ACV25289.1
PFAM: protein of unknown function DUF35; KEGG: dal:Dalk_3386 protein of unknown function DUF35.
       0.606
ACV25195.1
PFAM: metallophosphoesterase; KEGG: dol:Dole_2142 metallophosphoesterase.
       0.579
trm1
N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
       0.549
ACV24651.1
Hypothetical protein; KEGG: nam:NAMH_1389 putative curli production assembly/transport component CsgG subfamily.
       0.532
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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