Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24660.1PFAM: cation antiporter; KEGG: har:HEAR3011 pH adaptation potassium efflux system E transmembrane protein. (100 aa)    
Predicted Functional Partners:
ACV23897.1
PFAM: Na+/H+ antiporter MnhB subunit-related protein; KEGG: gbm:Gbem_1675 Na+/H+ antiporter MnhB subunit-related protein.
  
 
 0.998
ACV23899.1
PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: ech:ECH_0179 putative monovalent cation/H+ antiporter subunit D.
  
 
 0.995
ACV23900.1
PFAM: NADH-ubiquinone oxidoreductase chain 4L; KEGG: dal:Dalk_4921 NADH-ubiquinone oxidoreductase chain 4L.
  
 
 0.993
ACV23843.1
Multisubunit Na+/H+ antiporter MnhG subunit-like protein.
  
 
 0.991
ACV24405.1
Hypothetical protein.
  
 
 0.982
ACV24799.1
KEGG: gbm:Gbem_1676 hypothetical protein.
  
 
 0.927
ACV23894.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: nam:NAMH_1419 NADH dehydrogenase subunit I.
   
 
 0.881
pfdA
Prefoldin, alpha subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
       0.872
ACV23974.1
Formate hydrogenlyase subunit 4-like protein; KEGG: rhi:NGR_c10570 NADH dehydrogenase I chain H.
   
 
 0.849
ACV23967.1
KEGG: ppd:Ppro_2794 NADH dehydrogenase (ubiquinone), 30 kDa subunit.
  
 
 0.787
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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