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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24680.1PFAM: protein of unknown function DUF434; KEGG: sun:SUN_0694 hypothetical protein. (218 aa)    
Predicted Functional Partners:
ACV24679.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ppr:PBPRB0649 ferredoxin-type protein NapG.
       0.906
ACV24681.1
TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: dal:Dalk_3260 phosphodiesterase, MJ0936 family.
  
    0.835
purD
KEGG: sat:SYN_02439 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family.
       0.556
ACV24372.1
PFAM: major facilitator superfamily MFS_1; KEGG: dal:Dalk_2388 major facilitator superfamily MFS_1.
   
    0.434
ACV24689.1
PFAM: major facilitator superfamily MFS_1; KEGG: sat:SYN_02085 multidrug resistance protein B.
   
    0.434
ACV25221.1
PFAM: major facilitator superfamily MFS_1; KEGG: gbm:Gbem_3382 major facilitator superfamily MFS_1.
   
    0.434
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
     0.421
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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