Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rps27aePFAM: Ribosomal protein S27a; KEGG: ubiquitin; Belongs to the eukaryotic ribosomal protein eS31 family. (60 aa)    
Predicted Functional Partners:
rps24e
PFAM: Ribosomal protein S24e; KEGG: ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
 
 
 0.999
spt4
DNA-directed RNA polymerase subunit E, RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
  
    0.995
rpl40e
Hypothetical protein; Belongs to the eukaryotic ribosomal protein eL40 family.
  
   0.985
ACV24513.1
PFAM: Protein of unknown function DUF1610.
   
   0.981
rps17e
KEGG: 40S ribosomal protein S17-A; K02962 small subunit ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.
  
   0.976
rpl29
TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; KEGG: 60S ribosomal protein L35; K02918 large subunit ribosomal protein L35e; Belongs to the universal ribosomal protein uL29 family.
   
 
 0.975
rps3
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
   0.974
rpl15e
PFAM: Ribosomal protein L15e; KEGG: 60S ribosomal protein L15 (RPL15B); K02877 large subunit ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
   0.973
rpl37e
Ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.
   
   0.970
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
   0.970
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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