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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24695.1PFAM: CBS domain containing protein; peptidase M50; SMART: CBS domain containing protein; KEGG: afw:Anae109_3134 peptidase M50; Belongs to the peptidase M50B family. (338 aa)    
Predicted Functional Partners:
ACV25156.1
PFAM: NADPH-dependent FMN reductase; KEGG: dps:DP1259 iron-sulfur flavoprotein.
  
 
 0.893
ACV24084.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ftn:FTN_1526 dihydrolipoamide dehydrogenase.
  
 
 0.701
ACV24722.1
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
  
  
 0.591
ACV24919.1
PFAM: CheC domain protein; KEGG: gem:GM21_0635 CheC, inhibitor of MCP methylation.
  
 
 
 0.576
ACV24920.1
PFAM: CheC domain protein; KEGG: gem:GM21_0635 CheC, inhibitor of MCP methylation.
  
 
 
 0.574
cbiT
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
       0.558
ACV24697.1
Hypothetical protein.
       0.558
ACV25132.1
TIGRFAM: alpha-glucan phosphorylase; KEGG: nis:NIS_0944 glycogen/starch/alpha-glucan phosphorylase.
 
  
 0.428
ACV24222.1
TIGRFAM: methanogenesis marker protein 7; PFAM: Protein of unknown function UCP019164.
  
    0.423
guaAB
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 
 0.422
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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