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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24701.1PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: sat:SYN_00154 pyruvate:ferredoxin oxidoreductase beta subunit. (295 aa)    
Predicted Functional Partners:
ACV24699.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ecf:ECH74115_4176 putative oxidoreductase Fe-S binding subunit.
  
 
 0.999
ACV24700.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pmr:PMI2528 hydrogenase-4 component A.
  
 
 0.999
ACV24702.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sfu:Sfum_2794 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
 0.999
ACV24703.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sat:SYN_00156 pyruvate:ferredoxin oxidoreductase delta subunit.
 
 0.999
ACV24704.1
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: sat:SYN_00157 pyruvate:ferredoxin oxidoreductase gamma subunit.
 
 0.999
ACV23981.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dal:Dalk_1629 2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 0.995
ACV24600.1
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: gur:Gura_2189 pyruvate ferredoxin/flavodoxin oxidoreductase.
  
 
 0.950
cdhC
CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
  
 
 0.930
ACV24180.1
KEGG: nis:NIS_1773 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 0.927
cdhE
CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
  
 
 0.927
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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