close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24703.1TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sat:SYN_00156 pyruvate:ferredoxin oxidoreductase delta subunit. (86 aa)    
Predicted Functional Partners:
ACV24699.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ecf:ECH74115_4176 putative oxidoreductase Fe-S binding subunit.
  
 
  0.999
ACV24700.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pmr:PMI2528 hydrogenase-4 component A.
  
 
  0.999
ACV24701.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: sat:SYN_00154 pyruvate:ferredoxin oxidoreductase beta subunit.
 
 0.999
ACV24702.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sfu:Sfum_2794 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
 
 0.999
ACV24704.1
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: sat:SYN_00157 pyruvate:ferredoxin oxidoreductase gamma subunit.
 
 0.999
ACV24601.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: sfu:Sfum_3139 thiamine pyrophosphate enzyme domain protein TPP-binding.
  
 0.990
ACV23981.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: dal:Dalk_1629 2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 0.989
ACV25181.1
TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain protein; PFAM: CoA-binding domain protein; KEGG: dal:Dalk_1024 acetyl coenzyme A synthetase (ADP forming), alpha domain protein.
    
 0.932
ACV24148.1
TIGRFAM: acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: sfu:Sfum_3454 acetate--CoA ligase.
  
 
 0.925
ACV24606.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.924
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.