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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24720.1KEGG: cps:CPS_0308 UDP-N-acetylglucosamine 2-epimerase/UDP-N-acetyl-D-mannosamine dehydrogenase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase. (366 aa)    
Predicted Functional Partners:
ACV25103.1
TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerization; UDP-glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: geo:Geob_3227 nucleotide sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
 0.999
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
       0.835
ACV24719.1
PFAM: transcriptional regulator TrmB; KEGG: ecr:ECIAI1_1939 conserved hypothetical protein; CymJ protein, transcriptional regulator domain.
       0.803
ACV24140.1
PFAM: Glycosyl transferase, family 4, conserved region; KEGG: cje:Cj0433c phospho-N-acetylmuramoyl-pentapeptide-transferase.
  
  
 0.747
ACV24138.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: wbr:WGLp587 asparagine synthetase B.
 
  
 0.723
ACV23851.1
PFAM: polysaccharide biosynthesis protein; multi antimicrobial extrusion protein MatE; KEGG: pcr:Pcryo_0621 polysaccharide biosynthesis protein.
  
  
 0.688
ACV24348.1
PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein; multi antimicrobial extrusion protein MatE; KEGG: dol:Dole_1836 polysaccharide biosynthesis protein.
  
  
 0.688
ACV24717.1
TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: eba:p2A348 oxidoreductase, F420-dependent NADP reductase.
       0.640
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.631
ACV24345.1
PFAM: glycosyl transferase group 1; KEGG: cco:CCC13826_0993 putative cell division protease FtsH-like protein.
 
  
 0.593
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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