Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24720.1KEGG: cps:CPS_0308 UDP-N-acetylglucosamine 2-epimerase/UDP-N-acetyl-D-mannosamine dehydrogenase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase. (366 aa)    
Predicted Functional Partners:
ACV25103.1
TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerization; UDP-glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: geo:Geob_3227 nucleotide sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
 0.999
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
       0.953
ACV24598.1
PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: fph:Fphi_0366 UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase.
    
 0.936
ACV24355.1
TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: gme:Gmet_1159 UDP-glucose pyrophosphorylase.
  
 
 0.907
ACV24719.1
PFAM: transcriptional regulator TrmB; KEGG: ecr:ECIAI1_1939 conserved hypothetical protein; CymJ protein, transcriptional regulator domain.
       0.894
ACV24138.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: wbr:WGLp587 asparagine synthetase B.
 
  
 0.888
ACV24140.1
PFAM: Glycosyl transferase, family 4, conserved region; KEGG: cje:Cj0433c phospho-N-acetylmuramoyl-pentapeptide-transferase.
  
  
 0.708
ACV24348.1
PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein; multi antimicrobial extrusion protein MatE; KEGG: dol:Dole_1836 polysaccharide biosynthesis protein.
  
  
 0.680
ACV25212.1
PFAM: protein of unknown function DUF354; KEGG: nmu:Nmul_A0255 hypothetical protein.
 
    0.679
ACV23851.1
PFAM: polysaccharide biosynthesis protein; multi antimicrobial extrusion protein MatE; KEGG: pcr:Pcryo_0621 polysaccharide biosynthesis protein.
  
  
 0.678
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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