| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACV23959.1 | ACV24736.1 | Mefer_0117 | Mefer_0918 | Peptidase S16, Lon-like protease; KEGG: son:SO_3391 ATP-dependent protease, putative; TIGRFAM: peptidase S16, Lon-like protease; PFAM: peptidase S16 lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family. | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | 0.623 |
| ACV23959.1 | ACV24909.1 | Mefer_0117 | Mefer_1098 | Peptidase S16, Lon-like protease; KEGG: son:SO_3391 ATP-dependent protease, putative; TIGRFAM: peptidase S16, Lon-like protease; PFAM: peptidase S16 lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family. | PFAM: phosphoesterase RecJ domain protein; RNA binding S1 domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: dat:HRM2_01850 RecJ-like exonuclease (DnaJ-type Zn finger protein). | 0.801 |
| ACV23959.1 | nadK | Mefer_0117 | Mefer_0065 | Peptidase S16, Lon-like protease; KEGG: son:SO_3391 ATP-dependent protease, putative; TIGRFAM: peptidase S16, Lon-like protease; PFAM: peptidase S16 lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.684 |
| ACV23959.1 | pan | Mefer_0117 | Mefer_0150 | Peptidase S16, Lon-like protease; KEGG: son:SO_3391 ATP-dependent protease, putative; TIGRFAM: peptidase S16, Lon-like protease; PFAM: peptidase S16 lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.604 |
| ACV24401.1 | ACV24736.1 | Mefer_0580 | Mefer_0918 | KEGG: afr:AFE_0818 plasma-membrane proton-efflux P-type ATPase; TIGRFAM: plasma-membrane proton-efflux P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase type 3. | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | 0.708 |
| ACV24734.1 | ACV24735.1 | Mefer_0916 | Mefer_0917 | PFAM: peptidylprolyl isomerase FKBP-type; KEGG: nis:NIS_1212 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD. | PFAM: protein of unknown function DUF107; KEGG: hch:HCH_01497 membrane-bound serine protease (ClpP class). | 0.530 |
| ACV24734.1 | ACV24736.1 | Mefer_0916 | Mefer_0918 | PFAM: peptidylprolyl isomerase FKBP-type; KEGG: nis:NIS_1212 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD. | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | 0.605 |
| ACV24735.1 | ACV24734.1 | Mefer_0917 | Mefer_0916 | PFAM: protein of unknown function DUF107; KEGG: hch:HCH_01497 membrane-bound serine protease (ClpP class). | PFAM: peptidylprolyl isomerase FKBP-type; KEGG: nis:NIS_1212 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD. | 0.530 |
| ACV24735.1 | ACV24736.1 | Mefer_0917 | Mefer_0918 | PFAM: protein of unknown function DUF107; KEGG: hch:HCH_01497 membrane-bound serine protease (ClpP class). | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | 0.993 |
| ACV24736.1 | ACV23959.1 | Mefer_0918 | Mefer_0117 | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | Peptidase S16, Lon-like protease; KEGG: son:SO_3391 ATP-dependent protease, putative; TIGRFAM: peptidase S16, Lon-like protease; PFAM: peptidase S16 lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family. | 0.623 |
| ACV24736.1 | ACV24401.1 | Mefer_0918 | Mefer_0580 | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | KEGG: afr:AFE_0818 plasma-membrane proton-efflux P-type ATPase; TIGRFAM: plasma-membrane proton-efflux P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase type 3. | 0.708 |
| ACV24736.1 | ACV24734.1 | Mefer_0918 | Mefer_0916 | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | PFAM: peptidylprolyl isomerase FKBP-type; KEGG: nis:NIS_1212 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD. | 0.605 |
| ACV24736.1 | ACV24735.1 | Mefer_0918 | Mefer_0917 | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | PFAM: protein of unknown function DUF107; KEGG: hch:HCH_01497 membrane-bound serine protease (ClpP class). | 0.993 |
| ACV24736.1 | ACV24909.1 | Mefer_0918 | Mefer_1098 | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | PFAM: phosphoesterase RecJ domain protein; RNA binding S1 domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: dat:HRM2_01850 RecJ-like exonuclease (DnaJ-type Zn finger protein). | 0.736 |
| ACV24736.1 | ACV25046.1 | Mefer_0918 | Mefer_1237 | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: sat:SYN_01009 calcium-transporting ATPase. | 0.708 |
| ACV24736.1 | ACV25337.1 | Mefer_0918 | Mefer_1534 | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | PFAM: PilT protein domain protein; KH type 2 domain protein; K Homology, type 1, subgroup; SMART: Nucleotide binding protein PINc; KH domain protein; KEGG: vsp:VS_II0474 putative Flp pilus assembly protein TadA. | 0.642 |
| ACV24736.1 | asd-2 | Mefer_0918 | Mefer_1182 | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | Phosphatidylserine decarboxylase related protein; Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily. | 0.688 |
| ACV24736.1 | nadK | Mefer_0918 | Mefer_0065 | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.706 |
| ACV24736.1 | pan | Mefer_0918 | Mefer_0150 | PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.685 |
| ACV24909.1 | ACV23959.1 | Mefer_1098 | Mefer_0117 | PFAM: phosphoesterase RecJ domain protein; RNA binding S1 domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: dat:HRM2_01850 RecJ-like exonuclease (DnaJ-type Zn finger protein). | Peptidase S16, Lon-like protease; KEGG: son:SO_3391 ATP-dependent protease, putative; TIGRFAM: peptidase S16, Lon-like protease; PFAM: peptidase S16 lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family. | 0.801 |