Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACV24744.1PFAM: Protein of unknown function DUF361. (129 aa)    
Predicted Functional Partners:
ACV24741.1
PFAM: Protein of unknown function DUF361.
     
 0.971
ACV24743.1
PFAM: Protein of unknown function DUF515; KEGG: IMH1; potential GRIP domain protein similar to S. cerevisiae IMH1 (YLR309C); possible Golgi localization and role in protein transport under stress conditions.
     
 0.966
ACV24742.1
Hypothetical protein.
     
 0.950
ACV24745.1
PFAM: Peptidase A24A domain protein; peptidase A24A prepilin type IV; KEGG: hypothetical protein.
  
    0.826
ACV24746.1
PFAM: cysteine-rich small domain.
     
 0.812
ACV25035.1
Hypothetical protein.
  
  
 0.683
ACV24747.1
KEGG: gem:GM21_2548 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
       0.555
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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