Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24748.1PFAM: Protein of unknown function DUF166; KEGG: dal:Dalk_4871 protein of unknown function DUF166. (226 aa)    
Predicted Functional Partners:
ACV24041.1
TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit; PFAM: CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit.
 
     0.595
ACV24768.1
PFAM: glutamate synthase alpha subunit domain protein; KEGG: gsu:GSU1235 hypothetical protein.
 
     0.582
ACV24244.1
Conserved hypothetical protein.
  
     0.565
ACV24982.1
PFAM: protein of unknown function DUF98; KEGG: sde:Sde_3289 hypothetical protein.
  
     0.563
ACV24979.1
PFAM: Fe-S cluster domain protein; KEGG: geo:Geob_2527 Fe-S cluster domain protein.
  
     0.554
ACV24036.1
PFAM: Protein of unknown function DUF128; Ribonuclease R winged-helix domain protein; KEGG: sat:SYN_03243 putative cytoplasmic protein.
  
     0.523
ACV24037.1
TIGRFAM: pyridoxal phosphate enzyme; KEGG: spl:Spea_0442 selenocysteine synthase.
 
     0.519
ACV24411.1
PFAM: Oligosaccharyl transferase STT3 subunit; KEGG: nam:NAMH_1652 oligosaccharyl transferase, STT3 subunit.
  
     0.516
ACV24639.1
TIGRFAM: methanogenesis marker protein 9.
  
     0.516
cdhA
CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
 
     0.506
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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