Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24750.1TIGRFAM: H4MPT-linked C1 transfer pathway protein; PFAM: Hydantoinase/oxoprolinase; KEGG: noc:Noc_0256 S-layer protein, putative. (331 aa)    
Predicted Functional Partners:
ACV24514.1
PFAM: aspartate/glutamate/uridylate kinase; KEGG: noc:Noc_0254 amino acid kinase family protein.
 
  
 0.991
mfnD
Protein of unknown function DUF201; Catalyzes the formation of an amide bond between tyramine and the gamma carboxy group of L-glutamate. The enzyme also accepts phenylethylamine in vitro.
 
  
 0.991
mfnB
Protein of unknown function DUF556; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
 
   
 0.820
ACV23997.1
TIGRFAM: formylmethanofuran dehydrogenase subunit A; PFAM: Amidohydrolase 3; KEGG: noc:Noc_0024 DNA/RNA non-specific endonuclease.
 
   
 0.802
ftr
Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
     0.785
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family.
 
     0.780
ACV24280.1
PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mfa:Mfla_1656 triphosphoribosyl-dephospho-CoA protein.
 
   
 0.767
ACV24182.1
TIGRFAM: dihydropteroate synthase-related protein; PFAM: dihydropteroate synthase DHPS; KEGG: mei:Msip34_1684 dihydropteroate synthase DhpS.
 
   
 0.754
ACV23995.1
KEGG: mca:MCA2857 formylmethanofurane dehydrogenase subunit, putative; TIGRFAM: formylmethanofuran dehydrogenase subunit C; PFAM: glutamate synthase alpha subunit domain protein.
  
     0.742
ACV24847.1
PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: wbr:WGLp023 hypothetical protein.
 
     0.726
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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