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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24754.1TIGRFAM: methyl-coenzyme M reductase I operon protein C; PFAM: Methyl-coenzyme M reductase protein C. (200 aa)    
Predicted Functional Partners:
ACV24752.1
TIGRFAM: methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit.
 
 
 0.999
ACV24753.1
TIGRFAM: methyl-coenzyme M reductase operon protein D; PFAM: Methyl-coenzyme M reductase, protein D.
 
 
 0.999
ACV24755.1
TIGRFAM: methyl-coenzyme M reductase, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit.
 
 
 0.999
ACV24756.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
 
 0.999
ACV24635.1
TIGRFAM: methyl-coenzyme M reductase operon protein D; PFAM: Methyl-coenzyme M reductase, protein D.
 
 
 0.995
ACV24213.1
KEGG: ara:Arad_7321 peptide ABC transporter; TIGRFAM: methyl coenzyme M reductase system, component A2; PFAM: ABC transporter related; SMART: AAA ATPase.
 
  
 0.982
ACV24777.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ppd:Ppro_2905 ABC transporter related.
 
  
 0.958
mtrE
Tetrahydromethanopterin S-methyltransferase, subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
 
 
 0.905
mtrD
Tetrahydromethanopterin S-methyltransferase, subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
 
 
  0.891
mtrA
Tetrahydromethanopterin S-methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
 
 
 0.885
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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