Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24782.1TIGRFAM: CRISPR-associated protein, TM1812 family; CRISPR-associated protein DxTHG motif; PFAM: CRISPR-associated protein TM1812; KEGG: net:Neut_2223 CRISPR-associated TM1812 family protein. (247 aa)    
Predicted Functional Partners:
ACV24786.1
TIGRFAM: CRISPR-associated RAMP protein, Csm4 family; PFAM: protein of unknown function DUF324; KEGG: hypothetical protein.
 
   
 0.871
ACV24787.1
TIGRFAM: CRISPR-associated RAMP protein, Csm3 family; PFAM: protein of unknown function DUF324; KEGG: neu:NE0121 hypothetical protein.
 
   
 0.857
ACV24789.1
TIGRFAM: CRISPR-associated protein, Csm1 family; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: msu:MS1651 hypothetical protein.
 
   
 0.853
ACV24785.1
TIGRFAM: CRISPR-associated RAMP protein, Csm5 family; PFAM: protein of unknown function DUF324; KEGG: dol:Dole_0740 CRISPR-associated RAMP Csm5 family protein.
 
   
 0.835
ACV24781.1
KEGG: hypothetical protein.
       0.634
ACV24780.1
PFAM: protein of unknown function DUF711; KEGG: ppd:Ppro_0613 hypothetical protein; Belongs to the UPF0210 family.
  
    0.605
ACV24784.1
TIGRFAM: CRISPR-associated protein, MJ1666 family; CRISPR-associated protein DxTHG motif; PFAM: CRISPR-associated protein DxTHG; KEGG: p235 rhoptry protein E5.
       0.574
ACV24783.1
Hypothetical protein.
       0.568
ACV24788.1
TIGRFAM: CRISPR-associated protein, Csm2 family; PFAM: CRISPR-associated protein TM1810 domain protein.
       0.479
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.449
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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