STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24793.1Sep-tRNA; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (382 aa)    
Predicted Functional Partners:
sepS
O-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
  
 0.996
ACV25261.1
PFAM: Protein of unknown function DUF2100; KEGG: Ras guanine nucleotide exchange factor.
    
 
 0.911
ACV23861.1
PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: lip:LI0774 potassium transporter peripheral membrane component.
   
    0.825
ACV24791.1
Conserved hypothetical protein.
  
    0.748
ACV24792.1
PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: ank:AnaeK_2709 multiple antibiotic resistance (MarC)-related protein.
       0.738
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
   
 0.574
ACV23999.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfu:Sfum_0821 response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
   
 0.542
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily.
  
   
 0.537
ACV25125.1
TIGRFAM: methanogenesis marker protein 3; Belongs to the UPF0288 family.
  
    0.535
ACV25140.1
PFAM: protein of unknown function DUF169; KEGG: glo:Glov_0919 protein of unknown function DUF169.
 
     0.533
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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