STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24797.1PFAM: AIG2 family protein; KEGG: hypothetical protein. (107 aa)    
Predicted Functional Partners:
tgtA
Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
       0.789
dtdA
Protein of unknown function DUF516; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
  
     0.658
ACV24796.1
TIGRFAM: siroheme synthase; PFAM: TrkA-N domain protein; KEGG: tdn:Suden_1977 siroheme synthase CysG.
       0.615
ACV24799.1
KEGG: gbm:Gbem_1676 hypothetical protein.
       0.554
ACV24844.1
PFAM: Type II secretion system F domain; KEGG: pag:PLES_46811 TadB.
  
     0.498
ACV24849.1
Transcriptional regulator, MarR family; PFAM: regulatory protein ArsR; regulatory protein MarR; SMART: regulatory protein ArsR; KEGG: ank:AnaeK_0686 general secretion pathway protein-related protein.
  
     0.467
htpX
PFAM: peptidase M48 Ste24p; KEGG: dvm:DvMF_0946 peptidase M48 Ste24p; Belongs to the peptidase M48B family.
       0.446
ACV24794.1
TIGRFAM: methanogenesis marker 16 metalloprotein; PFAM: protein of unknown function DUF39; KEGG: dvm:DvMF_1464 protein of unknown function DUF39.
       0.438
ACV24800.1
PFAM: putative RNA methylase; THUMP domain protein; KEGG: buc:BU363 23S rRNA m(2)G2445 methyltransferase.
       0.416
taw3
Protein of unknown function DUF207; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family.
  
     0.413
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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