Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24801.1PFAM: Protein of unknown function DUF63. (267 aa)    
Predicted Functional Partners:
ACV24800.1
PFAM: putative RNA methylase; THUMP domain protein; KEGG: buc:BU363 23S rRNA m(2)G2445 methyltransferase.
       0.911
ACV24894.1
PFAM: protein of unknown function DUF95 transmembrane; KEGG: RNA methyltransferase, TrmH family protein.
 
   
 0.900
ACV25131.1
PFAM: Protein of unknown function UPF0179; Belongs to the UPF0179 family.
 
   
 0.887
egsA
3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
     
 0.681
ACV24122.1
PFAM: chromosome segregation and condensation protein ScpA; KEGG: hypothetical protein LOC691864.
  
     0.612
ACV24179.1
PFAM: inositol monophosphatase; KEGG: abu:Abu_0443 inositol-1-monophosphatase.
       0.602
ACV24373.1
S-layer domain protein-like protein; KEGG: bpt:Bpet0291 hypothetical protein.
  
     0.602
ACV24802.1
PFAM: protein of unknown function DUF81; KEGG: tcx:Tcr_1412 hypothetical protein.
       0.574
ACV24183.1
PFAM: protein of unknown function DUF75.
  
     0.573
ACV24064.1
S-layer domain protein-like protein.
  
     0.555
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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