Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24822.1PFAM: Radical SAM domain protein; KEGG: lpf:lpl0804 hypothetical protein. (286 aa)    
Predicted Functional Partners:
ACV24823.1
PFAM: protein of unknown function DUF366; KEGG: bba:Bd2230 hypothetical protein.
       0.921
ACV24821.1
TIGRFAM: methanogenesis marker protein 17; PFAM: Uncharacterized conserved protein UCP019464, methanogenesis.
       0.870
ACV24824.1
PFAM: permease; KEGG: nis:NIS_0906 hypothetical protein.
       0.774
ACV24149.1
PP-loop superfamily cell cycle control ATPase-like protein; KEGG: abu:Abu_0688 putative LPS biosynthesis protein WbpG.
 
   
 0.728
ACV24820.1
TIGRFAM: methanogenesis marker protein 15; CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: sfu:Sfum_1829 putative CoA-substrate-specific enzyme activase.
  
    0.641
pyrC
Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.631
ACV24819.1
PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: bxe:Bxe_A1411 putative thiamine-monophosphate kinase.
       0.465
ACV23852.1
KEGG: afw:Anae109_0787 beta-lactamase domain-containing protein.
 
  
 0.437
ACV24551.1
PFAM: peptidase U32; KEGG: dat:HRM2_21100 putative protease.
 
  
 0.432
ACV24465.1
PFAM: domain of unknown function DUF1745; KEGG: sat:SYN_01291 signal transduction histidine kinase.
 
    0.409
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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