STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV24823.1PFAM: protein of unknown function DUF366; KEGG: bba:Bd2230 hypothetical protein. (200 aa)    
Predicted Functional Partners:
ACV24822.1
PFAM: Radical SAM domain protein; KEGG: lpf:lpl0804 hypothetical protein.
       0.921
ACV24824.1
PFAM: permease; KEGG: nis:NIS_0906 hypothetical protein.
  
    0.794
ACV24821.1
TIGRFAM: methanogenesis marker protein 17; PFAM: Uncharacterized conserved protein UCP019464, methanogenesis.
 
     0.756
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
     0.753
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
     0.723
ACV23889.1
TIGRFAM: 6-pyruvoyl tetrahydropterin synthase; KEGG: hypothetical protein similar to 6-pyruvoyl tetrahydropterin synthase; K01737 6-pyruvoyl tetrahydrobiopterin synthase.
 
     0.690
ACV25146.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gsu:GSU2799 radical SAM domain-containing protein.
 
     0.643
ACV24820.1
TIGRFAM: methanogenesis marker protein 15; CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: sfu:Sfum_1829 putative CoA-substrate-specific enzyme activase.
       0.632
ACV24819.1
PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: bxe:Bxe_A1411 putative thiamine-monophosphate kinase.
       0.501
ACV24970.1
PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease family 2; KEGG: dma:DMR_37530 putative endonuclease IV.
  
    0.419
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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