Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24831.1PFAM: glucose-methanol-choline oxidoreductase; KEGG: ppr:PBPRB1949 hypothetical protein. (371 aa)    
Predicted Functional Partners:
ACV24832.1
TIGRFAM: methanogenesis marker protein 14; PFAM: conserved hypothetical protein.
       0.791
ACV23894.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: nam:NAMH_1419 NADH dehydrogenase subunit I.
 
   
 0.730
fae-hps
Formaldehyde-activating enzyme (Fae); Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family.
       0.717
ACV25126.1
PFAM: Aldehyde Dehydrogenase; KEGG: gur:Gura_1578 aldehyde dehydrogenase.
 
  
 0.694
ACV23887.1
PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide repeat; KEGG: TPR Domain containing protein.
 
 
 0.680
ACV25163.1
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide repeat; KEGG: hypothetical protein.
 
 
 0.678
ACV23974.1
Formate hydrogenlyase subunit 4-like protein; KEGG: rhi:NGR_c10570 NADH dehydrogenase I chain H.
  
     0.639
ACV25139.1
Phosphate uptake regulator, PhoU; PFAM: PhoU family protein; KEGG: cti:RALTA_A1971 negative regulator of PhoR/PhoB two-component regulator.
  
   
 0.633
ACV23963.1
KEGG: pmu:PM2006 hypothetical protein.
   
 0.629
ACV23965.1
Hypothetical protein; KEGG: pcr:Pcryo_0352 UDP-N-acetylglucosamine-peptide-N- acetylglucosaminyltransferase.
   
 0.629
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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