Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACV24833.1PFAM: protein of unknown function Met10; KEGG: hypothetical protein; K11438 protein arginine N-methyltransferase 7. (266 aa)    
Predicted Functional Partners:
ACV24837.1
PFAM: protein of unknown function DUF447.
       0.670
ACV25231.1
TIGRFAM: hydrogenase maturation protease HycI; hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: ppd:Ppro_0598 hydrogenase maturation protease.
       0.541
ACV24832.1
TIGRFAM: methanogenesis marker protein 14; PFAM: conserved hypothetical protein.
 
     0.524
ACV24831.1
PFAM: glucose-methanol-choline oxidoreductase; KEGG: ppr:PBPRB1949 hypothetical protein.
 
     0.460
ACV24658.1
PFAM: protein of unknown function DUF795; KEGG: pca:Pcar_2281 nucleotidyltransferase.
  
     0.437
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
Server load: low (16%) [HD]