STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oggDNA-(apurinic or apyrimidinic site) lyase; Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites); Belongs to the type-2 OGG1 family. (206 aa)    
Predicted Functional Partners:
ACV24980.1
PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; KEGG: gem:GM21_3590 HhH-GPD family protein.
  
   
 0.892
ACV24861.1
Putative transcriptional regulator, CopG family; PFAM: CopG domain protein DNA-binding domain protein; KEGG: sat:SYN_00477 nickel-responsive regulator.
       0.791
ACV24863.1
TIGRFAM: archaeoflavoprotein AfpA; PFAM: flavoprotein; KEGG: mmb:Mmol_0896 flavoprotein.
       0.709
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
      
 0.569
hcp
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
       0.483
ACV24740.1
KEGG: sat:SYN_01979 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein.
       0.461
ACV24859.1
KEGG: sat:SYN_00238 putative cytoplasmic protein.
       0.428
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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