Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24864.1PFAM: NADPH-dependent FMN reductase; KEGG: sat:SYN_02920 NADPH-dependent FMN reductase. (199 aa)    
Predicted Functional Partners:
ACV24865.1
PFAM: beta-lactamase domain protein; flavodoxin/nitric oxide synthase; KEGG: dal:Dalk_2373 beta-lactamase domain protein.
  
  
 0.766
ACV24863.1
TIGRFAM: archaeoflavoprotein AfpA; PFAM: flavoprotein; KEGG: mmb:Mmol_0896 flavoprotein.
 
    0.758
ACV24867.1
PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; KEGG: pca:Pcar_2346 rubrerythrin.
 
   
 0.735
ACV24866.1
KEGG: dde:Dde_1794 hypothetical protein.
  
    0.659
ACV24490.1
PFAM: protein of unknown function DUF106 transmembrane.
   
    0.543
ACV24868.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.495
ACV24183.1
PFAM: protein of unknown function DUF75.
 
    0.472
aroA-2
Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
 
  
 0.444
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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