Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24865.1PFAM: beta-lactamase domain protein; flavodoxin/nitric oxide synthase; KEGG: dal:Dalk_2373 beta-lactamase domain protein. (388 aa)    
Predicted Functional Partners:
ACV24866.1
KEGG: dde:Dde_1794 hypothetical protein.
 
    0.942
ACV24388.1
PFAM: pyridine nucleotide-disulphide oxidoreductase dimerization region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: afw:Anae109_0766 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
    
 0.839
ACV24867.1
PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; KEGG: pca:Pcar_2346 rubrerythrin.
 
  
 0.798
ACV24864.1
PFAM: NADPH-dependent FMN reductase; KEGG: sat:SYN_02920 NADPH-dependent FMN reductase.
  
  
 0.766
ACV24878.1
Hemerythrin-like metal-binding protein; Oxygen-binding protein. May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes. The oxygen- binding site contains two iron atoms; Belongs to the hemerythrin family.
  
  
 0.574
ACV24868.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.526
ACV24095.1
PFAM: CutA1 divalent ion tolerance protein; KEGG: GF15955 gene product from transcript GF15955-RA; K03926 periplasmic divalent cation tolerance protein.
  
    0.513
ACV24869.1
KEGG: dat:HRM2_41960 hypothetical protein.
  
  
 0.507
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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