Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACV24873.1TIGRFAM: CoB/CoM heterodisulfide reductase, subunit C; KEGG: sat:SYN_01643 Fe-S oxidoreductase. (193 aa)    
Predicted Functional Partners:
ACV24933.1
KEGG: nis:NIS_0688 succinate dehydrogenase/fumarate reductase, subunit C; TIGRFAM: CoB/CoM heterodisulfide reductase, subunit B; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein.
 
 0.999
ACV24076.1
4Fe-4S ferredoxin iron-sulfur binding domain protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 0.998
ACV24077.1
Contains selenocysteine; PFAM: methyl-viologen-reducing hydrogenase delta subunit; KEGG: dal:Dalk_3265 methyl-viologen-reducing hydrogenase delta subunit.
 
 0.996
ACV24078.1
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: gem:GM21_3973 NADH ubiquinone oxidoreductase 20 kDa subunit.
 
 0.991
ACV24473.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfu:Sfum_0822 formate dehydrogenase.
 
 0.990
ACV24079.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: dps:DP1013 methylviologen-reducing hydrogenase, alpha chain.
 
 0.989
ACV24472.1
Contains selenocysteine; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: ppd:Ppro_3520 formate dehydrogenase, alpha subunit.
   
 0.965
ACV24827.1
PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; KEGG: sfu:Sfum_2706 formate dehydrogenase, alpha subunit.
   
 0.965
ACV24934.1
TIGRFAM: CoB/CoM heterodisulfide reductase, subunit C; KEGG: dds:Ddes_2098 heterodisulfide reductase, C subunit.
  
  
 
0.903
ACV24872.1
PFAM: Carboxymuconolactone decarboxylase; KEGG: bpd:BURPS668_0604 4-carboxymuconolactone decarboxylase family protein.
  
    0.900
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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