Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACV24876.1PFAM: 4-vinyl reductase 4VR; KEGG: ppd:Ppro_0428 4-vinyl reductase, 4VR. (144 aa)    
Predicted Functional Partners:
ACV25306.1
PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; KEGG: bas:BUsg426 hypothetical protein.
 
  
 0.721
ACV24935.1
PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: aph:APH_0880 tRNA-i(6)A37 thiotransferase enzyme MiaB.
 
  
 0.615
ACV24104.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: hypothetical protein.
  
  
 0.553
ACV24572.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gur:Gura_1052 radical SAM domain-containing protein.
  
  
 0.553
ACV24668.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gsu:GSU3062 radical SAM domain-containing protein.
  
  
 0.553
ACV24877.1
PFAM: beta-lactamase domain protein; flavodoxin/nitric oxide synthase; KEGG: dal:Dalk_2373 beta-lactamase domain protein.
     
 0.553
ACV24964.1
PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mxa:MXAN_6449 B12 binding/radical SAM domain-containing protein.
  
  
 0.553
ACV24069.1
Conserved hypothetical protein.
  
     0.502
ACV24878.1
Hemerythrin-like metal-binding protein; Oxygen-binding protein. May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes. The oxygen- binding site contains two iron atoms; Belongs to the hemerythrin family.
 
     0.484
ACV23931.1
PFAM: Type II secretion system F domain.
 
     0.442
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
Server load: low (18%) [HD]